
Although cancer treatments are improving fast, prevention has so far been mostly about promoting a healthy lifestyle. But efforts to find preventive drugs and vaccines are starting to bear fruit(取得成果). New research shows that existing anti-inflammatory drugs hold promise(有希望) for preventing lung cancer.
尽管癌症治疗进展迅速,但预防迄今为止主要仍是通过倡导健康生活方式。然而,寻找预防性药物和疫苗的努力正开始取得成果。新研究表明,现有的抗炎药物有望用于预防肺癌。
Despite dramatic declines(大幅下降) in smoking, lung cancer is the most common cancer diagnosis globally. Smokers who quit face less danger but remain at higher lifetime risk than those who never smoked. People exposed at length(长时间地) to high levels of air pollution, for instance around busy roads in London, are at higher risk too.
尽管吸烟率大幅下降,肺癌仍是全球最常见的癌症诊断类别。戒烟者面临的危险较小,但终生风险仍高于从不吸烟者。长期暴露于高浓度空气污染(例如伦敦繁忙道路附近)的人群也面临更高的风险。
Now, an international team of 80 scientists has identified a molecular signature(分子特征) that predicts a higher risk of lung cancer. The group examined blood samples from nearly 50,000 people in the UK Biobank, a repository of data, samples and scans taken periodically from the same cohort(队列) of people. They used machine learning(机器学习) to analyse thousands of proteins in the samples and found a group of 14 whose levels increased five years or more before a lung cancer diagnosis.
如今,一个由80名科学家组成的国际团队识别出了一种可预测肺癌高风险特征的分子特征。该小组检查了来自英国生物样本库近5万人的血液样本——该库是一个定期从同一队列人群中收集数据、样本和扫描结果的资料库。他们利用机器学习分析了样本中的数千种蛋白质,发现其中14种蛋白质的水平在肺癌确诊前五年或更早就开始升高。